Rachel Baker Ph.D.

Education

• Postdoctotal Fellowship, Chemistry and Chemical Engineering, California Institute of Technology (2022 - 2023)
• PhD, Chemistry, University of Toronto (2017- 2022)
• BASc, Engineering Chemistry, Queen's University (2013 - 2017)

Journal Articles

Ton, T. N.; Baker, R. J.; Manthiram, K. (2024) Recent Progress in the Development of Electrode Materials for Electrochemical Carboxylation with CO2. J. Catal., 432: 115371. 

Harding, R. J.; Franzoni, I.; Mann, M. K.; Szewczyk, M. M.; Mirabi, B.; Ferreira de Freitas, R.; Owens, D. D. G.; Ackloo, S.; Scheremetjew, A.; Juarez-Ornelas, K. A.; Sanichar, R.; Baker, R. J.; Dank, C.; Brown, P. J.; Barsyte-Lovejoy, D.; Santhakumar, V.; Schapira, M.; Lautens, M.; Arrowsmith, C. H. (2023) Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6. J. Med. Chem., 66: 10273-10288.

Harrington, S.; Pyche, J.; Burns, A. R.; Spalholz, T.; Ryan, K. T.; Baker, R. J.; Ching, J.; Rufener, L.; Lautens, M.; Kulke, D.; Vernudachi, A.; Zamanian, M.; Deuther-Conrad, W.; Burst, P.; Roy, P. J. (2023). Nemacol is a Small Molecule Inhibitor of C. elegans Vesicular Acetylcholine Transporter with Anthelmintic Potential. Nature Communications. 14(1): 1816.

Burns, A. R.; Ross, R. J.; Kitner, M.; Castelli, J. M. P.; Volpatti, J. R.; et al. (2023). Selective Control of Parasitic Nematodes Using Bioactivated Nematicides. Nature. 618: 102–109. 

Harding, R.; Franzoni, I.; Mann, M.; Szewczyk, M.; Mirabi, B.; Owens, D.; Ackloo, S.; Scheremetjew, A.; Juarez-Ornelas, K.; Sanichar, R.; Baker, R.; Dank, C. et al. (2023). Discovery and Characterization of a Chemical Probe Targeting the Zincfinger Ubiquitin-binding Domain of HDAC6. Journal of Medicinal Chemistry.

Corbin, N.; Junor, G.; Ton, T. N.; Baker, R. J.; Manthiram, K. (2023). Toward Improving the Selectivity of Organic Halide Electrocarboxylation with Mechanistically Informed Solvent Selection. Journal of the American Chemical Society. 145(3): 1740-1748.

Baker, R. J.; Ching, J.; Hou, T. R.; Franzoni, I.; Lautens, M. (2022). Dearomative Cyclopropanation of Naphthols via Cyclopropene Ring-Opening. Angewandte Chemie International Edition. 61(8): e202116171.

Ross, R. J.; Jeyaseelan, R.; Lautens, M. (2020). Rhodium-Catalyzed Intermolecular Cyclopropanation of Benzofurans, Indoles, and Alkenes via Cyclopropene Ring Opening. Organic Letters. 22(12): 4838–4843.

Larin, E. M.; Loup, J.; Polishchuk, I.; Ross, R. J.; Whyte, A.; Lautens, M. (2020). Enantio- and Diastereoselective Conjugate Borylation/Mannich Cyclization. Chemical Science. 11(22): 5716-5723.

Zeidan, N.; Beisel, T.; Ross, R.; Lautens, M. (2018). Palladium-Catalyzed Arylation/Heteroarylation of Indoles: Access to 2,3- Functionalized Indolines. Organic Letters. 20(22): 7332-7335.

Bacon, S. L.; Ross, R. J.; Daugulis, A. J.; Parent, J. S. (2017). Imidazolium-based Polyionic Liquid Absorbents for Bioproduct Recovery. Green Chemistry. 19(21): 5203-5213.

Andrews, N. L. P.; Ross, R. J.; Munzke, D.; Van-Horne, C.; Brzezinski, A.; Barnes, J. A.; Reich, O.; Loock, H-P. (2016). In-fiber Mach-Zehnder Interferometer for Gas Refractive Index Measurements Based on a Hollow-core Photonic Crystal Fiber. Optic Express. 24(13): 14086-14099.

Molloy, B. M.; Johnson, K-A.; Ross, R. J.; Parent, J. S. (2016). Functional Group Tolerance of AOTEMPOmediated Peroxide Cure Chemistry. Polymer. 99: 598-604.

Patents

IMIDAZOTHIAZOLE COMPOUNDS AND METHODS FOR TREATING NEMATODE INFECTIONS IN PLANTS. Canada. 3,146,085. Patent Status: Pending Inventors: Burns, A., Lautens, M., Ross, R., and Roy, P.

COMPOUNDS AND METHODS FOR TREATING NEMATODE INFECTIONS, International Patent Application. Canada. PCT/CA2021/051257. Patent Status: Pending Inventors: Roy, P., Harrington, S., Burns, A., Pyche, J., Burns, A., Ross, R. and Lautens, M.

IMIDAZOTHIAZOLE COMPOUNDS AND METHODS FOR TREATING NEMATODE INFECTIONS IN PLANTS, International Patent Application. Canada. PCT/CA2022/050050. Patent Status: Pending Inventors: Burns, A., Lautens, M., Ross, R., and Roy, P.

Compounds and Methods for Treating Nematode Infections. United States of America. US 11,364,234. Patent Status: Granted/Issued Year Issued: 2022 Inventors: Roy, P.; Harrington, S.; Pyche, J.; Kulke, D.; Luciani, G. M.; Burns, A.; Lautens, M.; Ross, R.; Uehling, D.

IMIDAZOTHIAZOLE COMPOUNDS AND METHODS FOR TREATING NEMATODE INFECTIONS IN PLANTS. United States of America. 17/624,629. Patent Status: Pending Year Issued: 2020 Inventors: Burns, A., Lautens, M., Ross, R., and Roy, P.

COMPOUNDS AND METHODS FOR TREATING NEMATODE INFECTIONS. United States of America. US17/018,158. Patent Status: Granted/Issued Year Issued: 2020 Inventors: Roy, P., Harrington, S., Burns, A., Pyche, J., Burns, A., Ross, R. and Lautens, M.

• Robins Family Professorship of Engineering Chemistry Queen's University at Kingston:  Professorship endowed by DavosPharma founder and Kingston native Barry Robins, Sc’64 (2023)
• Second-place Poster Award at the CaRLa Winter School University of Heidelberg:  CaRLa (Catalysis Research Laboratory) based at the University of Heidelberg in Germany, offers a Winter School by invitation only to international researchers (2020)
• Alexander Graham Bell Canada Graduate Scholarship - Natural Sciences and Engineering Research Council of Canada (NSERC) (2019-22)
• Canadian Graduate Scholarships - Natural Sciences and Engineering Research Council of Canada (NSERC) Master’s Program Award (2018-19)